Mountain Sentinels is an international community that fosters global mountain sustainability by serving as a catalyst for innovative solutions and actions, aiming to bring together local and Indigenous knowledge, policy, industry, and transformational science, and elevating diverse voices through authentic partnerships. The rate of global warming is amplified at higher elevations; therefore, mountains are disproportionately threatened by climate change compared to lowlands. Our work aims to address critical sustainability issues, including adaptation to climate change, using an approach we call transformative science with society.